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What are the Causes of Conn’s Syndrome?

Most cases are random but some are passed down from a parent. Conn’s Syndrome could be due to a tumor on the adrenal gland (a benign cortical adenoma). It may be caused by an odd growth in both adrenal glands (known as a bilateral adrenal hyperplasia). Both health problems cause too much aldosterone to be released.

Sometimes excess aldosterone is caused by another health issue that lowers blood flow to the kidney. For example:

  • Fluid loss
  • Kidney artery narrowing
  • Heart failure
  • Shock
  • Liver disease
  • Pregnancy
  • Some kidney tumors

These cases are called "secondary hyperaldosteronism." This term is used because the excess hormone is not from a problem with the adrenal gland.