The exact cause of kidney cancer is not known. Wilms’ tumor has been linked to some birth defects.
Wilms’ tumor also has a greater chance of showing up in brothers and sisters. This suggests that it can be passed down in families.
There has been a lot of interest in the genetics of how renal tumors grow in children. Some specific changes in chromosomes have been linked to a greater risk for Wilms’ tumor and tumor growth. Experts hope that this might shed some light on how to treat this disease.