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What causes Testosterone Deficiency (TD)?

Some persons are born with conditions that cause Testosterone Deficiency (TD) such as:

  • Klinefelter syndrome 
  • Noonan syndrome
  • Ambiguous genitalia (when the sex organs develop in ways that are not typical looking)

Some men may develop Low-T because of conditions like these:

  • Damage to testicles by accident
  • Removal of testicles because of cancer
  • Chemotherapy or radiation
  • Pituitary gland disease leading to hormone deficiency
  • Infection
  • Autoimmune disease (when the body makes antibodies that attack its own cells)

Basically, if your testicles keep making less testosterone than normal, your blood levels of testosterone will fall. Many men who develop TD have Low-T levels linked to:

  • Aging
  • Obesity
  • Metabolic syndrome (high blood pressure, high blood sugar, unhealthy cholesterol levels, and belly fat)
  • Use of medications such as antidepressants and narcotic pain medications

Men with certain health problems also tend to have low testosterone. Some of these are:

  • HIV (about 30 out of 100 also have low testosterone)
  • AIDS (about 50 out of 100 also have low testosterone)