Penile tumors are thought to be caused by body fluids that get trapped in the foreskin. If they aren’t washed away on a routine basis, they can have cancer-causing effects. Older men and smokers are more likely to get penile cancer. Conditions like AIDS can lead to penile cancer.
Another possible cause may be the human papilloma virus (HPV). HPV is a virus passed through sex. Antibodies to HPV-16 have been found in many patients with penile cancer. HPV is known to play a role in cervical cancer as well. For more information please review our Sexually Transmitted Disease article.
Men who keep clean with good genital hygiene and who are circumcised are much less likely to get penile cancer.