If you have advanced prostate cancer or are taking hormonal therapy, your provider may suggest calcium or Vitamin D for your bones. Some drugs can also help strengthen and protect your bones. These include Denosumab (Xgeva®) and Zoledronic Acid (Zometa®). Both help prevent bad side effects from the cancer growing in your bones. These side effects can include bone thinning, bone breaks and bone pain.
Radium-223 (Xofigo®) is another new treatment approved for men whose mCRPC has spread to their bones. This treatment is injected in your veins. It collects in the bones where cancer has spread and is growing fast.
Once in the bones it gives off small amounts of radiation that can only travel short distances. This can target radiation to the exact areas of the bone where cancer cells are growing. Radium-223 has been shown to help men live longer.
With Radium-223, your PSA level does not show how well you are responding. Although your PSA level may increase, this does not mean that the treatment is not working.
Updated August 2018