The prostate is a small walnut shaped gland in the pelvis of men. It is located next to the bladder and can be examined by getting a digital rectal exam. Prostate cancer is a form of cancer that develops in the prostate gland. It is the second-leading cause of cancer deaths for men in the U.S. About 1 in 9 men will be diagnosed with prostate cancer in their lifetime. This year, nearly 175,000 men will be diagnosed with prostate cancer.
Growths in the prostate can be benign (not cancer) or malignant (cancer).
Benign growths (like benign prostatic hypertrophy (BPH):
- Are rarely a threat to life
- Don't invade the tissues around them
- Don't spread to other parts of the body
- Can be removed and can grow back very slowly (but usually don't grow back)
Malignant growths (prostate cancer):
- May sometimes be a threat to life
- Can spread to nearby organs and tissues (such as the bladder or rectum)
- Can spread (metastasize) to other parts of the body (like lymph nodes or bone)
- Often can be removed but sometimes grow back
Prostate cancer cells can spread by breaking away from a prostate tumor. They can travel through blood vessels or lymph nodes to reach other parts of the body. After spreading, cancer cells may attach to other tissues and grow to form new tumors, causing damage where they land.
When prostate cancer spreads from its original place to another part of the body, the new tumor has the same kind of abnormal cells and the same name as the primary (original) tumor. For example, if prostate cancer spreads to the bones, the cancer cells in the bones are actually prostate cancer cells. The disease is metastatic prostate cancer, not bone cancer. For that reason, it's treated as prostate cancer in bone.
To understand prostate cancer, it helps to know how the prostate normally works.
The prostate and seminal vesicles are part of the male reproductive system. The prostate is about the size of a walnut and weighs about one ounce. The seminal vesicles are two much smaller paired glands. These glands are attached to each side of the prostate. Some have said that the seminal vesicles look like rabbit ears attached to the prostate. The prostate is below the bladder and in front of the rectum. The prostate surrounds the urethra. The urethra is a tube that carries urine from the bladder out through the penis. This is why men with an enlarged prostate have difficulty urinating. It can disrupt the flow of urine from the bladder.
The main job of the prostate and seminal vesicles is to make fluid to bathe semen. During ejaculation, sperm is made in the testicles, and then moves to the urethra. At the same time, fluid from the prostate and the seminal vesicles also moves into the urethra. This mixture of semen and fluid from the prostate and seminal vesicles forms the ejaculate that passes through the urethra and out of the penis.
When prostate cancer occurs, it starts in the prostate gland and occasionally spreads to the seminal vesicles.
Updated January 2019